Mouse Anti-NACAD Recombinant Antibody (H-4) (CBMAB-N1053-WJ)

This product is a Mouse antibody that recognizes NACAD. The antibody H-4 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NACAD antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse, Rat

Clone

H-4

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Human, Mouse, Rat

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

NAC alpha domain containing

Introduction

May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). May bind to nascent polypeptide chains as they emerge from the ribosome and block their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).

Entrez Gene ID

Human	23148
Mouse	192950
Rat	289786

UniProt ID

Human	O15069
Mouse	Q5SWP3
Rat	F1M6E5

Alternative Names

NAC Alpha Domain Containing; KIAA0363;

Function

Biological Process

Protein targeting to membrane Source: GO_Central

Cellular Location

Nucleus
Cytoplasm

References

Yuan, Y., Zhao, Y., & Ma, D. (2023). NACAD: A Noise-Adaptive Context-Aware Detector for Remote Sensing Small Objects. IEEE Transactions on Geoscience and Remote Sensing.

Reddy, R., Chertman, W., Efimenko, I., Kresch, E., Khodamoradi, K., & Ramasamy, R. (2022). Whole exome sequencing identifies a rare mutation in NACAD as a possible cause of covid orchitis in brothers. The Journal of Sexual Medicine, 19(4), S29-S30.

Ramsoomair, C. K., Seetharam, D., Moorthy, B. T., Zhang, F., & Ramasamy, R. (2022). Mechanistic Insights into a Rare Mutation in Nacad as a Possible Cause of Covid Orchitis. Fertility and Sterility, 118(4), e24.

Reddy, R., Iakov, E., Khodamoradi, K., Chertman, W., Arora, H., Diaz, P., & Ramasamy, R. (2022). MP37-11 WHOLE EXOME SEQUENCING IDENTIFIES A RARE MUTATION IN NACAD AS A POSSIBLE CAUSE OF COVID ORCHITIS IN BROTHERS. The Journal of Urology, 207(Supplement 5), e612.

Reddy, R., Chertman, W., Kresch, E., Khodamoradi, K., Efimenko, I., & Ramasamy, R. (2021). WHOLE EXOME SEQUENCING IDENTIFIES A RARE NONSENSE MUTATION IN NACAD AS A POSSIBLE CAUSE OF COVID ORCHITIS IN BROTHERS. Fertility and Sterility, 116(3), e349-e350.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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