Mouse Anti-NAF1 Recombinant Antibody (5C4) (CBMAB-N1073-WJ)

This product is a Mouse antibody that recognizes NAF1. The antibody 5C4 can be used for immunoassay techniques such as: FuncS, FC.
See all NAF1 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

5C4

Antibody Isotype

IgG1

Application

FuncS, FC

Basic Information

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Preservative

0.09% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Nuclear Assembly Factor 1 Ribonucleoprotein

Introduction

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.

Entrez Gene ID

92345

UniProt ID

Q96HR8

Alternative Names

Nuclear Assembly Factor 1 Ribonucleoprotein; Nuclear Assembly Factor 1 Homolog (S. Cerevisiae); HNAF1;

Function

Lysosomal transporter which is essential for liver homeostasis. Required to maintain stability and lysosomal localization of GLMP.

Biological Process

Protein localization to lysosome Source: UniProtKB
Protein stabilization Source: UniProtKB

Cellular Location

Lysosome membrane

PTM

Not N-glycosylated.

References

Olsson, J. B., Gugerel, M. B., Jessen, S. B., Jørgensen, J., Gögenur, I., Hansen, C., ... & Troelsen, J. T. (2022). Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity. Plos one, 17(9), e0274033.

Wei, J., Yang, Q., Shi, J., Shi, B., Ji, M., & Hou, P. (2019). Increased expression of NAF1 contributes to malignant phenotypes of glioma cells through promoting protein synthesis and associates with poor patient survival. Oncogenesis, 8(4), 25.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-NAF1 Recombinant Antibody (5C4)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote

Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: