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Mouse Anti-NDRG3 Recombinant Antibody (H-11) (CBMAB-N1587-WJ)

This product is a Mouse antibody that recognizes NDRG3. The antibody H-11 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NDRG3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
H-11
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
N-myc downstream regulated gene 3
Introduction
NDRG3 (NDRG Family Member 3) is a Protein Coding gene. Diseases associated with NDRG3 include Charcot-Marie-Tooth Disease, Type 4D and Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive. Among its related pathways are PI3K / Akt Signaling and Apoptosis and Autophagy. An important paralog of this gene is NDRG1.
Entrez Gene ID
Human57446
Mouse29812
Rat296318
UniProt ID
HumanQ9UGV2
MouseQ9QYF9
RatQ6AYR2
Alternative Names
NDRG Family Member 3; N-Myc Downstream-Regulated Gene 3 Protein;
Biological Process
Cell differentiation Source: UniProtKB
Negative regulation of cell growth Source: UniProtKB
Signal transduction Source: GO_Central
Spermatogenesis Source: UniProtKB
Cellular Location
Extracellular region or secreted
extracellular exosome
Other locations
cytoplasm

Song, X., Gu, L., Yang, Q., Wu, J., Chen, J., Tian, X., ... & Chen, L. (2023). Thermosensitive injectable hydrogel loaded with hypoxia-induced exosomes maintains chondrocyte phenotype through NDRG3-mediated hypoxic response. Chinese Chemical Letters, 34(8), 108079.

Sohn, H. A., Lee, D. C., Park, A., Kang, M., Yoon, B. H., Lee, C. H., ... & Yeom, Y. I. (2022). Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers. Cells, 11(9), 1536.

Luo, Z., Gong, T., Li, W., & Tao, W. (2022). LncRNA Meg3 promotes oxygen and glucose deprivation injury by decreasing angiogenesis in hBMECs by targeting the miR‑122‑5p/NDRG3 axis. Experimental and Therapeutic Medicine, 24(4), 1-10.

Wang, J., Wang, J., Quan, J., Liu, J., Tian, L., & Dong, C. (2022). Relationship between serum NDRG3 and papillary thyroid carcinoma. Frontiers in Endocrinology, 13, 1091462.

Ma, W., Zhao, X., Xue, N., Gao, Y., & Xu, Q. (2021). The LINC01410/miR‐122‐5p/NDRG3 axis is involved in the proliferation and migration of osteosarcoma cells. Iubmb Life, 73(4), 705-717.

Yang, Z., Wu, W., Ou, P., Wu, M., Zeng, F., Zhou, B., & Wu, S. (2021). MiR-122-5p knockdown protects against APAP-mediated liver injury through up-regulating NDRG3. Molecular and Cellular Biochemistry, 476, 1257-1267.

Kim, K. R., Kim, K. A., Park, J. S., Jang, J. Y., Choi, Y., Lee, H. H., ... & Han, B. W. (2020). Structural and biophysical analyses of human N-Myc downstream-regulated gene 3 (NDRG3) protein. Biomolecules, 10(1), 90.

Kim, M. C., Park, M. H., Kang, S. H., & Bae, Y. K. (2019). NDRG3 protein expression is associated with aggressive biologic phenotype and unfavorable outcome in patients with invasive breast cancer. International Journal of Clinical and Experimental Pathology, 12(10), 3886.

Shi, J., Zheng, H., & Yuan, L. (2019). High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of β-catenin. BMB reports, 52(7), 451.

Yu, J., Shen, J., Qiao, X., Cao, L., Yang, Z., Ye, H., ... & Gong, Z. (2019). SNHG20/miR‑140‑5p/NDRG3 axis contributes to 5‑fluorouracil resistance in gastric cancer. Oncology letters, 18(2), 1337-1343.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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