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Mouse Anti-NDUFA5 Recombinant Antibody (1E8) (CBMAB-N1605-WJ)

This product is a Mouse antibody that recognizes NDUFA5. The antibody 1E8 can be used for immunoassay techniques such as: WB, IF .
See all NDUFA5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1E8
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
0.47 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NADH:Ubiquinone Oxidoreductase Subunit A5
Introduction
This nuclear gene encodes a conserved protein that comprises the B13 subunit of complex I of the mitochondrial respiratory chain. The encoded protein localizes to the inner mitochondrial membrane, where it is thought to aid in the transfer of electrons from NADH to ubiquinone. Alternative splicing results in multiple transcript variants. There are numerous pseudogenes of this gene on chromosomes 1, 3, 6, 8, 9, 11, 12, and 16. [provided by RefSeq, Apr 2014]
Entrez Gene ID
4698
UniProt ID
Q16718
Alternative Names
NADH:Ubiquinone Oxidoreductase Subunit A5; NADH-Ubiquinone Oxidoreductase 13 KDa-B Subunit; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 5, 13kDa; Complex I 13kDa Subunit B; Complex I Subunit B13; Type I Dehydrogenase; Ubiquinone Reductase; CI-13KD-B; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 5 (13kD, B13);
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Biological Process
Aerobic respiration Source: ComplexPortal
Mitochondrial ATP synthesis coupled proton transport Source: ComplexPortal
Mitochondrial electron transport, NADH to ubiquinone Source: UniProtKB
Mitochondrial respiratory chain complex I assembly Source: UniProtKB
Respiratory electron transport chain Source: GO_Central
Cellular Location
Mitochondrion inner membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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