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Mouse Anti-NDUFB6 Recombinant Antibody (21C11BC11) (CBMAB-N1657-WJ)

This product is a Mouse antibody that recognizes NDUFB6. The antibody 21C11BC11 can be used for immunoassay techniques such as: WB, FC.
See all NDUFB6 antibodies
Published Data
Fig.1 Western blot for the subunits of Complex 1. Subunits analyzed were NDUFB6 (distal part of membrane arm), NDUFV2 (distal part of matrix arm), NDUFA10 (middle part of membrane arm), MTND1 (proximal part of membrane arm) and the housekeeping β-actin protein.
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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Cattle, Human
Clone
21C11BC11
Antibody Isotype
IgG2b
Application
WB, FC

Basic Information

Specificity
Mouse, Rat, Cattle, Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NADH:Ubiquinone Oxidoreductase Subunit B6
Introduction
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jan 2011]
Entrez Gene ID
Human4712
Mouse230075
Rat297990
Cattle327665
UniProt ID
HumanO95139
MouseQ3UIU2
RatD3ZZ21
CattleQ02367
Alternative Names
NADH:Ubiquinone Oxidoreductase Subunit B6; NADH-Ubiquinone Oxidoreductase B17 Subunit; NADH Dehydrogenase (Ubiquinone) 1 Beta Subcomplex, 6, 17kDa; Complex I, Mitochondrial Respiratory Chain, B17 Subunit; NADH-Ubiquinone Oxidoreductase Beta Subunit, 6; Complex I-B17;
Function
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Biological Process
Aerobic respiration Source: ComplexPortal
Mitochondrial ATP synthesis coupled electron transport Source: CAFA
Mitochondrial ATP synthesis coupled proton transport Source: ComplexPortal
Mitochondrial electron transport, NADH to ubiquinone Source: ProtInc
Mitochondrial respiratory chain complex I assembly Source: UniProtKB
Cellular Location
Mitochondrion inner membrane
Topology
Helical: 68-86
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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