Mouse Anti-NEUROD6 Recombinant Antibody (1B5) (CBMAB-N2055-WJ)

Name: Mouse Anti-NEUROD6 Recombinant Antibody (1B5)
SKU: CBMAB-N2055-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1B5

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

neurogenic differentiation 6

Introduction

This gene is a member of the NEUROD family of basic helix-loop-helix transcription factors. The encoded protein may be involved in the development and differentiation of the nervous system. [provided by RefSeq, Nov 2012]

Entrez Gene ID

63974

UniProt ID

Q96NK8

Alternative Names

Neuronal Differentiation 6; Class A Basic Helix-Loop-Helix Protein 2; Protein Atonal Homolog 2; BHLHa2; Atoh2; Neurogenic Differentiation Factor 6; Neurogenic Differentiation 6;

Function

Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity).

Biological Process

Dentate gyrus development Source: Ensembl
Neuron differentiation Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

Bimpisidis, Z., Serra, G. P., König, N., & Wallén-Mackenzie, Å. (2023). Increased sucrose consumption in mice gene-targeted for Vmat2 selectively in NeuroD6-positive neurons of the ventral tegmental area. Frontiers in Molecular Neuroscience, 16, 1069834.

Angelova, A., Platel, J. C., Béclin, C., Cremer, H., & Coré, N. (2019). Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation. Journal of Comparative Neurology, 527(7), 1245-1260.

Bimpisidis, Z., König, N., Stagkourakis, S., Zell, V., Vlcek, B., Dumas, S., ... & Wallén-Mackenzie, Å. (2019). The NeuroD6 subtype of VTA neurons contributes to psychostimulant sensitization and behavioral reinforcement. Eneuro, 6(3).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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