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Mouse Anti-NFYC Recombinant Antibody (C-2) (CBMAB-N2336-WJ)

This product is a Mouse antibody that recognizes NFYC. The antibody C-2 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NFYC antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
C-2
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NFYC
Introduction
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Entrez Gene ID
4802
UniProt ID
Q13952
Alternative Names
Nuclear Transcription Factor Y Subunit Gamma; Nuclear Transcription Factor Y Subunit C; CAAT Box DNA-Binding Protein Subunit C; Nuclear Transcription Factor Y, Gamma; Transactivator HSM-1/2; NF-YC; CCAAT Transcription Binding Factor Subunit Gamma; Histone H1 Transcription Factor Large Subunit 2A; Transcription Factor NF-Y, C Subunit;
Function
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
Biological Process
Histone H3-K4 trimethylationManual Assertion Based On ExperimentIDA:ComplexPortal
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:ComplexPortal
Protein foldingManual Assertion Based On ExperimentTAS:ProtInc
Regulation of histone acetylationManual Assertion Based On ExperimentIDA:ComplexPortal
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentTAS:ProtInc
Regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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