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Mouse Anti-NIPSNAP1 Recombinant Antibody (H-9) (CBMAB-N2480-WJ)

This product is a Mouse antibody that recognizes NIPSNAP1. The antibody H-9 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NIPSNAP1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
H-9
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human, Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Nipsnap Homolog 1
Introduction
This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. A similar protein in mice inhibits the calcium channel TRPV6, and is also localized to the inner mitochondrial membrane where it may play a role in mitochondrial DNA maintenance. A pseudogene of this gene is located on the short arm of chromosome 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Entrez Gene ID
Human8508
Mouse18082
Rat360971
UniProt ID
HumanQ9BPW8
MouseO55125
RatG3V728
Alternative Names
Nipsnap Homolog 1; 4-Nitrophenylphosphatase Domain And Non-Neuronal SNAP25-Like 1; NIPSNAP, C. Elegans, Homolog 1; Nipsnap Homolog 1 (C. Elegans); NipSnap1;
Biological Process
Sensory perception of painManual Assertion Based On ExperimentIBA:GO_Central

Yamamoto, S., Ogasawara, N., Mitsuhashi, Y., Takano, K., & Yokota, S. I. (2024). The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control. Scientific Reports, 14(1), 2354.

Gao, E., Sun, X., Thorne, R. F., Zhang, X. D., Li, J., Shao, F., ... & Wu, M. (2023). NIPSNAP1 directs dual mechanisms to restrain senescence in cancer cells. Journal of Translational Medicine, 21(1), 1-24.

Li, R., Wang, Z., Wang, Y., Sun, R., Zou, B., Tian, X., ... & Yao, J. (2023). SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1. Journal of Cellular Physiology, 238(9), 2090-2102.

Liu, Y., Qu, Y., Cheng, C., Tsai, P. Y., Edwards, K., Xue, S., ... & Barrow, J. J. (2023). Nipsnap1—A regulatory factor required for long-term maintenance of non-shivering thermogenesis. Molecular Metabolism, 75, 101770.

Li, S., Zhou, Y., Gu, X., Zhang, X., & Jia, Z. (2021). NLRX1/FUNDC1/NIPSNAP1‐2 axis regulates mitophagy and alleviates intestinal ischaemia/reperfusion injury. Cell Proliferation, 54(3), e12986.

Attar, M. (2019). The Role of NIPSNAP1 in Oxidative Stress.

Abudu, Y. P., Pankiv, S., Mathai, B. J., Lamark, T., Johansen, T., & Simonsen, A. (2019). NIPSNAP1 and NIPSNAP2 act as “eat me” signals to allow sustained recruitment of autophagy receptors during mitophagy. Autophagy, 15(10), 1845-1847.

Abudu, Y. P., Pankiv, S., Mathai, B. J., Lystad, A. H., Bindesbøll, C., Brenne, H. B., ... & Simonsen, A. (2019). NIPSNAP1 and NIPSNAP2 act as “eat me” signals for mitophagy. Developmental cell, 49(4), 509-525.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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