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Mouse Anti-NME7 Recombinant Antibody (1A11) (CBMAB-N2797-WJ)

This product is a Mouse antibody that recognizes NME7. The antibody 1A11 can be used for immunoassay techniques such as: ELISA.
See all NME7 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A11
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
NME/NM23 Family Member 7
Introduction
This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Entrez Gene ID
29922
UniProt ID
Q9Y5B8
Alternative Names
NME/NM23 Family Member 7; Non-Metastatic Cells 7, Protein Expressed In (Nucleoside-Diphosphate Kinase); Cilia And Flagella Associated Protein 67; NDP Kinase 7; EC 2.7.4.6; Nm23-H7;
Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Biological Process
CTP biosynthetic processIEA:InterPro
GTP biosynthetic processIEA:InterPro
UTP biosynthetic processIEA:InterPro
Cellular Location
Centrosome
Cytosol
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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