Mouse Anti-NME7 Recombinant Antibody (1A11) (CBMAB-N2797-WJ)

Name: Mouse Anti-NME7 Recombinant Antibody (1A11)
SKU: CBMAB-N2797-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1A11

Application

ELISA

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

NME/NM23 Family Member 7

Introduction

This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Entrez Gene ID

29922

UniProt ID

Q9Y5B8

Alternative Names

NME/NM23 Family Member 7; Non-Metastatic Cells 7, Protein Expressed In (Nucleoside-Diphosphate Kinase); Cilia And Flagella Associated Protein 67; NDP Kinase 7; EC 2.7.4.6; Nm23-H7;

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Biological Process

CTP biosynthetic processIEA:InterPro
GTP biosynthetic processIEA:InterPro
UTP biosynthetic processIEA:InterPro

Cellular Location

Centrosome
Cytosol

Adam, K., Ning, J., Reina, J., & Hunter, T. (2020). NME/NM23/NDPK and histidine phosphorylation. International journal of molecular sciences, 21(16), 5848.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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