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Mouse Anti-NNAT Recombinant Antibody (1B9) (CBMAB-N2836-WJ)

This product is a Mouse antibody that recognizes NNAT. The antibody 1B9 can be used for immunoassay techniques such as: ELISA.
See all NNAT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B9
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
neuronatin
Introduction
The protein encoded by this gene is a proteolipid that may be involved in the regulation of ion channels during brain development. The encoded protein may also play a role in forming and maintaining the structure of the nervous system. This gene is found within an intron of another gene, bladder cancer associated protein, but on the opposite strand. This gene is imprinted and is expressed only from the paternal allele. [provided by RefSeq, Apr 2016]
Entrez Gene ID
4826
UniProt ID
Q16517
Alternative Names
Neuronatin; Peg5;
Function
May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels.
Biological Process
Brain developmentManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of insulin secretionManual Assertion Based On ExperimentIBA:GO_Central
Protein lipoylationManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm

Rudolph, A., Stengel, A., Suhs, M., Schaper, S., Wölk, E., Rose, M., & Hofmann, T. (2023). Circulating Neuronatin Levels Are Positively Associated with BMI and Body Fat Mass but Not with Psychological Parameters. Nutrients, 15(16), 3657.

Xing, P., Hong, L., Yan, G., Tan, B., Qiao, J., Wang, S., ... & Gu, T. (2022). Neuronatin gene expression levels affect foetal growth and development by regulating glucose transport in porcine placenta. Gene, 809, 146051.

Braun, J., Teng, A., Geromella, M., Ryan, C., Fenech, R., MacPherson, R., ... & Fajardo, V. (2021). Neuronatin Promotes SERCA Uncoupling and Its Expression is Inversely Associated with High Fat Diet Induced Weight Gain in vivo. The FASEB Journal, 35.

Pieper, W., Ignatov, A., Kalinski, T., Haybaeck, J., Czapiewski, P., & Nass, N. (2021). The predictive potential of Neuronatin for neoadjuvant chemotherapy of breast cancer. Cancer Biomarkers, 32(2), 161-173.

Braun, J. L., Teng, A. C., Geromella, M. S., Ryan, C. R., Fenech, R. K., MacPherson, R. E., ... & Fajardo, V. A. (2021). Neuronatin promotes SERCA uncoupling and its expression is altered in skeletal muscles of high‐fat diet‐fed mice. FEBS letters, 595(22), 2756-2767.

Cimino, I., Rimmington, D., Tung, Y. L., Lawler, K., Larraufie, P., Kay, R. G., ... & Coll, A. P. (2021). Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity. Scientific Reports, 11(1), 17571.

Braun, J. L., Geromella, M. S., Hamstra, S. I., & Fajardo, V. A. (2020). Neuronatin regulates whole‐body metabolism: is thermogenesis involved?. FASEB BioAdvances, 2(10), 579.

Kanno, N., Fujiwara, K., Yoshida, S., Kato, T., & Kato, Y. (2020). Dynamic changes in the localization of neuronatin-positive cells during neurogenesis in the embryonic rat brain. Cells Tissues Organs, 207(3-4), 127-137.

Lombardi, L., Blanchet, C., Poirier, K., Lebrun, N., Ramoz, N., Moro, M. R., ... & Bienvenu, T. (2019). Anorexia nervosa is associated with Neuronatin variants. Psychiatric Genetics, 29(4), 103-110.

Kanno, N., Yoshida, S., Kato, T., & Kato, Y. (2019). Characteristic localization of neuronatin in rat testis, hair follicle, tongue, and pancreas. Journal of Histochemistry & Cytochemistry, 67(7), 495-509.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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