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Mouse Anti-NPFF Recombinant Antibody (7F12) (CBMAB-A6071-LY)

The product is antibody recognizes NPFF. The antibody 7F12 immunoassay techniques such as: WB, ELISA.
See all NPFF antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7F12
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
NPFF (AAI04235.1, 1 a.a. ~ 116 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
neuropeptide FF-amide peptide precursor
Introduction
FMFRamide-related protein precursor plays a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. FMRFAL encodes a preproprotein which is cleaved to form two active peptides with similar function. [provided by RefSeq]
Entrez Gene ID
8620
UniProt ID
O15130
Alternative Names
FMRFAL
Function
Morphine modulating peptides. Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas. Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
Biological Process
Chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Excitatory postsynaptic potentialManual Assertion Based On ExperimentIBA:GO_Central
Neuropeptide signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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