Rat Anti-NTNG1 Recombinant Antibody (CBWJN-1577) (CBMAB-N3767-WJ)

Name: Rat Anti-NTNG1 Recombinant Antibody (CBWJN-1577)
SKU: CBMAB-N3767-WJ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

CBWJN-1577

Application

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Netrin G1

Introduction

This gene encodes a preproprotein that is processed into a secreted protein containing eukaroytic growth factor (EGF)-like domains. This protein acts to guide axon growth during neuronal development. Polymorphisms in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2015]

Entrez Gene ID

80883

UniProt ID

Q8R4G0

Alternative Names

Netrin G1; Netrin-G1; Lmnt1; Axon Guidance Molecule; Netrin G1f; Laminet 1; Laminet-1; KIAA0976;

Function

Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.

Biological Process

Animal organ morphogenesisManual Assertion Based On ExperimentIBA:GO_Central
AxonogenesisISS:UniProtKB
Basement membrane assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Modulation of chemical synaptic transmissionIEA:Ensembl
Regulation of neuron migrationISS:UniProtKB
Regulation of neuron projection arborizationISS:UniProtKB
Regulation of neuron projection developmentISS:UniProtKB
Substrate adhesion-dependent cell spreadingManual Assertion Based On ExperimentIBA:GO_Central
Synaptic membrane adhesionManual Assertion Based On ExperimentIGI:SynGO-UCL
Tissue developmentManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

PTM

N-glycosylated.

Gao, X., Lin, Y., Huang, X., Lu, C., Luo, W., Zeng, D., ... & Ye, J. (2024). Comprehensive analysis of the role of Netrin G1 (NTNG1) in hepatocellular carcinoma cells. European Journal of Pharmacology, 963, 176262.

Gao, X., Lin, Y., Xiang, B., Ma, L., Su, T., Liang, R., & Ye, J. (2021). Study of RNA38 reverses apatinib resistance in hepatocellular carcinoma via regulating NTNG1. HPB, 23, S496.

Fang, S., Luo, Y., Zhang, Y., Wang, H., Liu, Q., Li, X., & Yu, T. (2021). NTNG1 Modulates cisplatin resistance in epithelial ovarian cancer cells via the GAS6/AXL/Akt Pathway. Frontiers in Cell and Developmental Biology, 9, 652325.

Vattathil, S. M., Liu, Y., Harerimana, N. V., Lori, A., Gerasimov, E. S., Beach, T. G., ... & Wingo, T. S. (2021). A genetic study of cerebral atherosclerosis reveals novel associations with NTNG1 and CNOT3. Genes, 12(6), 815.

Lehrer, S., & Rheinstein, P. H. (2020). Sars-CoV-2 orf1b gene sequence in the ntng1 gene on human chromosome 1. in vivo, 34(3 suppl), 1629-1632.

Tang, Y. L., Dong, X. Y., Zeng, Z. G., & Feng, Z. (2020). Gene expression-based analysis identified NTNG1 and HGF as biomarkers for diabetic kidney disease. Medicine, 99(1), e18596.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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