Mouse Anti-NUDT22 Recombinant Antibody (B-11) (CBMAB-N3904-WJ)

This product is a Mouse antibody that recognizes NUDT22. The antibody B-11 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all NUDT22 antibodies

Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

B-11

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat, Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Nudix Hydrolase 22

Introduction

NUDT22 (Nudix Hydrolase 22) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include hydrolase activity.

Entrez Gene ID

Human	84304
Mouse	68323
Rat	293703

UniProt ID

Human	Q9BRQ3
Mouse	Q9DD16
Rat	Q6P9U1

Alternative Names

Nudix Hydrolase 22; Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 22; Nudix Motif 22;

Function

Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose.

Cellular Location

Nucleoplasm

References

Walter, M., Mayr, F., Hanna, B. M., Cookson, V., Mortusewicz, O., Helleday, T., & Herr, P. (2023). NUDT22 promotes cancer growth through pyrimidine salvage. Oncogene, 42(16), 1282-1293.

Walter, M. (2022). Exploitation of the UDP-glucose hydrolase NUDT22 as novel target in cancer therapy (Doctoral dissertation, University of Sheffield).

Walter, M., Mayr, F., Hanna, B. M. F., Cookson, V., Mortusewicz, O., Helleday, T., & Herr, P. (2022). NUDT22 promotes cancer growth through pyrimidine salvage and the TCA cycle.

Walter, M., Homan, E., Koolmeister, T., Almlöf, I., Mortusewicz, O., Helleday, T., & Herr, P. (2021, January). Development of small molecule NUDT22 inhibitors for uses in cancer. In Medical Sciences Forum (Vol. 3, No. 1, p. 1). MDPI.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Mouse Anti-NUDT22 Recombinant Antibody (H-9)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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