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Mouse Anti-NXF3 Recombinant Antibody (2C7) (CBMAB-N4060-WJ)

This product is a Mouse antibody that recognizes NXF3. The antibody 2C7 can be used for immunoassay techniques such as: ELISA, WB.
See all NXF3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2C7
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nuclear RNA export factor 3
Introduction
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
Entrez Gene ID
56000
UniProt ID
Q9H4D5
Alternative Names
Nuclear RNA Export Factor 3; TAP-Like Protein 3; TAPL-3; TAPL3;
Function
May function as a tissue-specific nuclear mRNA export factor.
Biological Process
mRNA export from nucleusManual Assertion Based On ExperimentIDA:UniProtKB
Poly(A)+ mRNA export from nucleusManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Cytoplasm
Shuttles between the nucleus and the cytoplasm.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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