Rabbit Anti-OLIG3 Recombinant Antibody (CBXO-0151) (CBMAB-O0386-CQ)

Name: Rabbit Anti-OLIG3 Recombinant Antibody (CBXO-0151)
SKU: CBMAB-O0386-CQ
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Rabbit

Specificity

Human

Clone

CBXO-0151

Antibody Isotype

IgG

Application

WB, IF

Basic Information

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

OLIGODENDROCYTE TRANSCRIPTION FACTOR 3

Introduction

OLIG3 (Oligodendrocyte Transcription Factor 3) is a Protein Coding gene. Among its related pathways are Neural Crest Differentiation. Gene Ontology (GO) annotations related to this gene include protein dimerization activity and RNA polymerase II transcription corepressor activity. An important paralog of this gene is OLIG2.

Entrez Gene ID

167826

UniProt ID

Q7RTU3

Alternative Names

Oligodendrocyte Transcription Factor 3; Class E Basic Helix-Loop-Helix Protein 20; Class B Basic Helix-Loop-Helix Protein 7; BHLHe20; Bhlhb7; Oligo3

Function

May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.

Biological Process

Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Spinal cord motor neuron cell fate specificationIEA:Ensembl
Spinal cord motor neuron migrationIEA:Ensembl

Cellular Location

Nucleus

More Infomation

References

Lowenstein, E. D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A. E., Epifanova, E., ... & Hernandez-Miranda, L. R. (2021). Olig3 regulates early cerebellar development. Elife, 10, e64684.

Lowenstein, E. D., Rusanova, A., Stelzer, J., Hernaiz-Llorens, M., Schroer, A. E., Epifanova, E., ... & Hernandez-Miranda, L. R. (2020). Olig3 acts as a master regulator of cerebellar development. bioRxiv, 2020-10.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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