Rabbit Anti-OR1A1 Recombinant Antibody (CBXO-0132) (CBMAB-O0501-CQ)

Name: Rabbit Anti-OR1A1 Recombinant Antibody (CBXO-0132)
SKU: CBMAB-O0501-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

CBXO-0132

Application

WB, IP

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.309 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Olfactory Receptor Family 1 Subfamily A Member 1

Introduction

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Entrez Gene ID

8383

UniProt ID

Q9P1Q5

Alternative Names

Olfactory Receptor Family 1 Subfamily A Member 1; Olfactory Receptor OR17-11; Olfactory Receptor 17-7; OR17-7; Olfactory Receptor, Family 1, Subfamily A, Member 1; Olfactory Receptor 1A1

Function

Odorant receptor.

Cellular Location

Cell membrane

Topology

Extracellular: 1-25
Helical: 26-49
Cytoplasmic: 50-57
Helical: 58-79
Extracellular: 80-100
Helical: 101-120
Cytoplasmic: 121-139
Helical: 140-158
Extracellular: 159-195
Helical: 196-218
Cytoplasmic: 219-235
Helical: 236-258
Extracellular: 259-270
Helical: 271-290
Cytoplasmic: 291-309

Ke, S., Zhang, S., Liu, D., Zhao, T., Lou, X., Cheng, S., ... & Li, H. (2024). Ectopic OR1A1 activation ameliorates hepatic lipid deposition through AMPK/SREBP-1/FASN pathway by three monoterpenes. Journal of Functional Foods, 115, 106097.

Khemis, I. B., Aouaini, F., Bukhari, L., Alruwaili, A., Znaidia, S., & Lamine, A. B. (2023). Investigation of the adsorption mechanism of two nitro musk odorants on OR1A1: Advanced modeling and thermodynamic study. Journal of Molecular Liquids, 390, 123017.

He, M., Liu, W., Zhang, C., Liu, Y., Zhuang, H., & O’Hagan, D. (2022). Selectively fluorinated citronellol analogues support a hydrogen bonding donor interaction with the human OR1A1 olfactory receptor. Organic Letters, 24(24), 4415-4420.

Khemis, I. B., Bouzid, M., Mechi, N., & Lamine, A. B. (2021). Statistical physics modeling and interpretation of the adsorption of enantiomeric terpenes onto the human olfactory receptor OR1A1. International Journal of Biological Macromolecules, 171, 428-434.

Khemis, I. B., & Lamine, A. B. (2021). Adsorption of 2-phenylethanethiol on two broadly tuned human olfactory receptors OR1A1 and OR2W1: Interpretation of the effect of copper ions via statistical physics monolayer adsorption model. Journal of Molecular Liquids, 341, 116926.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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