Mouse Anti-PANK3 Recombinant Antibody (3C4) (CBMAB-P0730-YC)

Name: Mouse Anti-PANK3 Recombinant Antibody (3C4)
SKU: CBMAB-P0730-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

3C4

Application

FC, WB

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

pantothenate kinase 3

Introduction

PANK3 is a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.

Entrez Gene ID

79646

UniProt ID

Q9H999

Alternative Names

Pantothenate Kinase 3; Pantothenic Acid Kinase 3; EC 2.7.1.33; HPanK3;

Function

Catalyzes the phosphorylation of pantothenate to generate 4'-phosphopantothenate in the first and rate-determining step of coenzyme A (CoA) synthesis.

Biological Process

Coenzyme A biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
PhosphorylationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm

Khadka, S., Vien, L., Leonard, P., Bover, L., & Muller, F. (2022). Generation and validation of an anti-human PANK3 mouse monoclonal antibody. Biomolecules, 12(9), 1323.

Hao, Z., Wang, J., Luo, Y., Hu, J., Liu, X., Li, S., ... & Zhen, H. (2022). MicroRNA-200c affects milk fat synthesis by targeting PANK3 in ovine mammary epithelial cells. International Journal of Molecular Sciences, 23(24), 15601.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PANK3 Recombinant Antibody (3D7) (CAT#: CBMAB-P0731-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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