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Mouse Anti-PAX9 Recombinant Antibody (3B8) (CBMAB-P0903-YC)

Provided herein is a Mouse monoclonal antibody against Human Paired Box 9. The antibody can be used for immunoassay techniques, such as ELISA, IHC-P, WB.
See all PAX9 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3B8
Antibody Isotype
IgG2a
Application
ELISA, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Paired Box 9
Introduction
PAX9 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3.
Entrez Gene ID
5083
UniProt ID
P55771
Alternative Names
Paired Box 9; Paired Box Protein Pax-9; Paired Domain Gene 9; Paired Box Gene 9; STHAG3;
Function
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
Biological Process
Anatomical structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Cellular response to growth factor stimulusIEA:Ensembl
Endoderm developmentIEA:Ensembl
Face morphogenesisIEA:Ensembl
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
OdontogenesisIEA:Ensembl
Regulation of odontogenesisIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
Involvement in disease
Tooth agenesis, selective, 3 (STHAG3):
A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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