Mouse Anti-PCDH20 Recombinant Antibody (2C3) (CBMAB-P0971-YC)

Name: Mouse Anti-PCDH20 Recombinant Antibody (2C3)
SKU: CBMAB-P0971-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2C3

Application

ELISA, WB

Immunogen

PCDH20 (NP_073754, 395-495 aa) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

protocadherin 20

Introduction

PCDH20 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.

Entrez Gene ID

64881

UniProt ID

Q8N6Y1

Alternative Names

Protocadherin 20; PCDH13; Protocadherin 13; Protocadherin-20; Protocadherin-13;

Function

Potential calcium-dependent cell-adhesion protein.

Biological Process

Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro

Cellular Location

Cell membrane

Topology

Extracellular: 61-890
Helical: 891-911
Cytoplasmic: 912-951

Ning, Y., Deng, C., Li, C., Peng, W., Yan, C., Ran, J., ... & Xiang, T. (2022). PCDH20 inhibits esophageal squamous cell carcinoma proliferation and migration by suppression of the mitogen-activated protein kinase 9/AKT/β-catenin pathway. Frontiers in Oncology, 12, 937716.

Gong, Z., & Hu, G. (2019). PCDH20 acts as a tumour-suppressor gene through the Wnt/β-catenin signalling pathway in hypopharyngeal squamous cell carcinoma. Cancer Biomarkers, 26(2), 209-217.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PCDH20 Recombinant Antibody (1B7) (CAT#: CBMAB-P0970-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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