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Mouse Anti-Pcdhb1 Recombinant Antibody (S144-32) (CBMAB-P1000-YC)

Provided herein is a Mouse monoclonal antibody against Mouse Protocadherin Beta 1. The antibody can be used for immunoassay techniques, such as ICC, IF, WB.
See all Pcdhb1 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat
Clone
S144-32
Antibody Isotype
IgG2b
Application
ICC, IF, WB

Basic Information

Specificity
Mouse, Rat
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Protocadherin Beta 1
Introduction
Pcdhb1 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Entrez Gene ID
Mouse93872
Rat364841
UniProt ID
MouseQ91Y08
RatF2Z3R5
Alternative Names
Protocadherin Beta 1; PCDH-Beta-1; Protocadherin Beta-1; PCDH-BETA1;
Function
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 29-691
Helical: 692-712
Cytoplasmic: 713-818
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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