Sign in or Register   Sign in or Register
  |  

Mouse Anti-PCDHGB2 Recombinant Antibody (6E9) (CBMAB-P1026-YC)

Provided herein is a Mouse monoclonal antibody against Human Protocadherin Gamma Subfamily B, 2. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PCDHGB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6E9
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PCDHGB2 (NP_061746, 94-199 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protocadherin gamma subfamily B, 2
Introduction
PCDHGB2 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Entrez Gene ID
56103
UniProt ID
Q9Y5G2
Alternative Names
Protocadherin Gamma Subfamily B, 2; PCDH-GAMMA-B2; Protocadherin Gamma-B2;
Function
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Biological Process
Cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Homophilic cell adhesion via plasma membrane adhesion moleculesIEA:InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 31-691
Helical: 692-712
Cytoplasmic: 713-931
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PCDHGB2 Recombinant Antibody (6E9)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare