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Mouse Anti-PDAP1 Recombinant Antibody (3B10) (CBMAB-P1122-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3B10
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PDAP1 (AAH00684, 1-181 aa) full length recombinant protein with GST tag. Immunogen sequence: MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PKKEKKSLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGPKELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAARKKEEE RKAKDDATLS GKRMQSLSLN K
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-181

Target

Full Name
PDGFA associated protein 1
Introduction
PDAP1 is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity.
Entrez Gene ID
11333
UniProt ID
Q13442
Alternative Names
PDGFA Associated Protein 1; PDGF-Associated Protein; HASPP28; PAP1; PAP; 28 KDa Heat-And Acid-Stable Phosphoprotein; PDGFA-Associated Protein 1; PDGF Associated Protein;
Function
Enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB.
Biological Process
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
cytosol
extracellular region
ficolin-1-rich granule lumen
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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