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Mouse Anti-PDCD5 Recombinant Antibody (CBYC-P240) (CBMAB-P1163-YC)

Provided herein is a Mouse monoclonal antibody against Human Programmed Cell Death 5. The antibody can be used for immunoassay techniques, such as WB, IHC.
See all PDCD5 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYC-P240
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
E. coli-derived Recombinant human PDCD5, Ala2-Tyr125
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS with trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Programmed Cell Death 5
Introduction
PDCD5 is a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12
Entrez Gene ID
Human9141
Mouse56330
Rat292814
UniProt ID
HumanO14737
MouseP56812
RatD4ADF5
Alternative Names
Programmed Cell Death 5; TF-1 Cell Apoptosis-Related Protein 19; TF1 Cell Apoptosis-Related Gene 19; TFAR19 Novel Apoptosis-Related; TFAR19; Programmed Cell Death Protein 5; Protein TFAR19;
Function
May function in the process of apoptosis.
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cellular response to transforming growth factor beta stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of chaperone-mediated protein foldingManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of apoptotic processManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein insertion into mitochondrial outer membraneManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of release of cytochrome c from mitochondriaManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
cytoplasm
cytosol
extracellular exosome
nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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