Mouse Anti-PDCD5 Recombinant Antibody (CBYC-P240) (CBMAB-P1163-YC)

Name: Mouse Anti-PDCD5 Recombinant Antibody (CBYC-P240)
SKU: CBMAB-P1163-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYC-P240

Application

WB, IHC

Immunogen

E. coli-derived Recombinant human PDCD5, Ala2-Tyr125

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized from PBS with trehalose

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Programmed Cell Death 5

Introduction

PDCD5 is a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12

Entrez Gene ID

Human	9141
Mouse	56330
Rat	292814

UniProt ID

Human	O14737
Mouse	P56812
Rat	D4ADF5

Alternative Names

Programmed Cell Death 5; TF-1 Cell Apoptosis-Related Protein 19; TF1 Cell Apoptosis-Related Gene 19; TFAR19 Novel Apoptosis-Related; TFAR19; Programmed Cell Death Protein 5; Protein TFAR19;

Function

May function in the process of apoptosis.

Biological Process

Apoptotic processIEA:UniProtKB-KW
Cellular response to transforming growth factor beta stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of cell population proliferationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of chaperone-mediated protein foldingManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of apoptotic processManual Assertion Based On ExperimentIMP:FlyBase
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of gene expressionManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein insertion into mitochondrial outer membraneManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of release of cytochrome c from mitochondriaManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

cytoplasm
cytosol
extracellular exosome
nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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