Mouse Anti-PDLIM7 Recombinant Antibody (CBT4502) (V2LY-0625-LY1697)

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Tested Data
Request for COA
Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT4502
Application
IHC, ICC, FC
Immunogen
Purified recombinant fragment of human PDLIM7 (AA: 86-280) expressed in HEK293-6e cells supernatant.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
PDZ and LIM domain 7 (enigma)
Entrez Gene ID
UniProt ID
Function
May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).
Biological Process
Actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Cell differentiationIEA:UniProtKB-KW
Heart developmentManual Assertion Based On ExperimentIBA:GO_Central
Muscle structure developmentManual Assertion Based On ExperimentIBA:GO_Central
OssificationIEA:UniProtKB-KW
Positive regulation of osteoblast differentiationIEA:Ensembl
Receptor-mediated endocytosisManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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