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Mouse Anti-PDS5B Recombinant Antibody (2030D32a) (CBMAB-P1365-YC)

Provided herein is a Mouse monoclonal antibody against Human PDS5 Cohesin Associated Factor B. The antibody can be used for immunoassay techniques, such as Dot.
See all PDS5B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2030D32a
Antibody Isotype
IgG1
Application
Dot

Basic Information

Immunogen
Recombinant human Pds5, Regulator Of Cohesion Maintenance, Homolog B (S.Cerevisiae) (Pds5 B)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PDS5 Cohesin Associated Factor B
Introduction
PDS5B is a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
Entrez Gene ID
23047
UniProt ID
Q9NTI5
Alternative Names
PDS5 Cohesin Associated Factor B; Androgen-Induced Proliferation Inhibitor; Androgen-Induced Prostate Proliferative Shutoff-Associated Protein AS3; APRIN; AS3; PDS5, Regulator Of Cohesion Maintenance, Homolog B (S. Cerevisiae);
Function
Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.
Biological Process
Cell divisionIEA:UniProtKB-KW
Cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Mitotic sister chromatid cohesionManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of cell population proliferationManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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