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Mouse Anti-PFKP Recombinant Antibody (3A12) (CBMAB-P1519-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphofructokinase, Platelet. The antibody can be used for immunoassay techniques, such as FC, IF, IHC, WB.
See all PFKP antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3A12
Antibody Isotype
IgG1
Application
FC, IF, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phosphofructokinase, platelet
Introduction
PFKP is a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung.
Entrez Gene ID
UniProt ID
Alternative Names
Phosphofructokinase, Platelet; Phosphofructo-1-Kinase Isozyme C;-Phosphofructokinase Type C; Phosphohexokinase; EC 2.7.1.11; ATP-PFK; PFK-C; PFK-P;
Function
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
Biological Process
Canonical glycolysisManual Assertion Based On ExperimentIBA:GO_Central
Cellular response to leukemia inhibitory factorIEA:Ensembl
Fructose 1,6-bisphosphate metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Fructose 6-phosphate metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
PTM
Phosphorylation at Ser-386 promotes interaction with ATG4B.
GlcNAcylation decreases enzyme activity.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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