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  |  

Mouse Anti-PGC Recombinant Antibody (15j162) (CBMAB-P1561-YC)

Provided herein is a Mouse monoclonal antibody against Human Progastricsin. The antibody can be used for immunoassay techniques, such as ELISA, ICC, IHC, WB.
See all PGC antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
15j162
Antibody Isotype
IgG
Application
ELISA, ICC, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid in PBS, pH 7.2, 0.02% sodium azide, 50% glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Progastricsin
Introduction
PGC is an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. A pseudogene of this gene is found on chromosome 1.
Entrez Gene ID
5225
UniProt ID
P20142
Alternative Names
Progastricsin; Pepsinogen C; EC 3.4.23.3; Progastricsin (Pepsinogen C); Pepsinogen Group II; Preprogastricsin;
Function
Hydrolyzes a variety of proteins.
Biological Process
DigestionManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of antibacterial peptide productionManual Assertion Based On ExperimentIMP:UniProtKB
ProteolysisManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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