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Mouse Anti-PGLYRP4 Recombinant Antibody (CBYC-P330) (CBMAB-P1591-YC)

Provided herein is a Mouse monoclonal antibody against Human Peptidoglycan Recognition Protein 4. The antibody can be used for immunoassay techniques, such as WB, IP.
See all PGLYRP4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P330
Antibody Isotype
IgG2b
Application
WB, IP

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived Recombinant human PGLYRP4/PGRP-I beta, Asp18-His373
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized from PBS with trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Peptidoglycan Recognition Protein 4
Introduction
Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria.
Entrez Gene ID
57115
UniProt ID
Q96LB8
Alternative Names
Peptidoglycan Recognition Protein 4; Peptidoglycan Recognition Protein Intermediate Beta; Peptidoglycan Recognition Protein I-Beta; PGLYRPIbeta; PGRP-I-Beta; PGRPIB; Peptidoglycan Recognition Protein I Beta Precursor; PGRP-Ibeta; SBBI67;
Function
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIDA:UniProtKB
Defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Detection of bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Innate immune response1 PublicationNAS:UniProtKB
Killing of cells of another organismManual Assertion Based On ExperimentIDA:UniProtKB
Peptidoglycan catabolic processIEA:InterPro
Cellular Location
Secreted
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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