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Mouse Anti-PHACTR3 Recombinant Antibody (4A5) (CBMAB-P1637-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
4A5
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PHACTR3 (NP_542403.1, 92-179 aa) partial recombinant protein with GST tag. Immunogen sequence: TSALEKKMAG RQGREELIKK GLLEMMEQDA ESKTCNPDGG PRSVQSEPPT PKSETLTSED AQPGSPLATG TDQVSLDKPL SSAAHLDD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 92-179

Target

Full Name
phosphatase and actin regulator 3
Introduction
PHACTR3 is a member of the phosphatase and actin regulator protein family. The encoded protein is associated with the nuclear scaffold in proliferating cells, and binds to actin and the catalytic subunit of protein phosphatase-1, suggesting that it functions as a regulatory subunit of protein phosphatase-1.
Entrez Gene ID
116154
UniProt ID
Q96KR7
Alternative Names
Phosphatase And Actin Regulator 3; Protein Phosphatase 1, Regulatory Subunit 123; Scaffold-Associated PP1-Inhibiting Protein; C20orf101; SCAPININ; SCAPIN1; Chromosome 20 Open Reading Frame 101; PPP1R123; H17739;
Biological Process
Actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus matrix
Localized to the nuclear matrix-intermediate filament scaffold. Isoform 2 is also found in some cytoplasmic extensions.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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