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Mouse Anti-PHKG1 Recombinant Antibody (2B4) (CBMAB-P1686-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphorylase Kinase Catalytic Subunit Gamma 1. The antibody can be used for immunoassay techniques, such as ELISA, IHC-P, WB.
See all PHKG1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2B4
Antibody Isotype
IgG2a, κ
Application
ELISA, IHC-P, WB

Basic Information

Immunogen
PHKG1 (AAH51327, 1-388 aa) full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phosphorylase kinase, gamma 1 (muscle)
Introduction
PHKG1 is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12.
Entrez Gene ID
UniProt ID
Alternative Names
Phosphorylase Kinase Catalytic Subunit Gamma 1; Phosphorylase Kinase, Gamma 1 (Muscle); Serine/Threonine-Protein Kinase PHKG1; Phosphorylase Kinase Subunit Gamma-1; EC 2.7.11.19; PHK-Gamma-M; PHKG;
Function
Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).
Biological Process
Carbohydrate metabolic process1 PublicationNAS:ProtInc
Glycogen biosynthetic processIEA:InterPro
Cellular Location
cytosol
phosphorylase kinase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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