Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser886 of human GEF-H1 protein.
Human, Mouse, Rat
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]
Rho/Rac Guanine Nucleotide Exchange Factor 2; Rho/Rac Guanine Nucleotide Exchange Factor (GEF) 2; Proliferating Cell Nucleolar Antigen P40; Guanine Nucleotide Exchange Factor H1; Microtubule-Regulated Rho-GEF; GEF-H1; LFP40;