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Recombinant Rabbit Anti-Phospho-EIF2S1-S51 Antibody (CBAb262) (CBMAB-Ab262-LY)

The product is antibody recognizes Phospho-EIF2S1-S51. The antibody immunoassay techniques such as: WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200.
Host Animal
Rabbit
Application
WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200
Immunogen
A phospho specific peptide corresponding to residues surrounding S51 of human eIF2a
Antibody Isotype
IgG
Specificity
Human
Cross Reactivity
Human, Mouse, Rat
Clone
CBAb262
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha.
Alternative Name
EIF2S1; EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A; eukaryotic translation initiation factor 2 subunit 1
Entrez Gene ID
UniProt ID
Cat CBMAB-Ab262-LY
Conjugates
Size
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