Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr353 of human ezrin protein.
Human, Monkey, Dog
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
Ezrin; Villin 2 (Ezrin); Cytovillin 2; VIL2; P81; Epididymis Secretory Protein Li 105;