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Recombinant Rabbit Anti-Phospho-RB1-S807 Antibody (CBAb267) (CBMAB-Ab267-LY)

The product is antibody recognizes Phospho-RB1-S807. The antibody immunoassay techniques such as: WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200.
Host Species
Rabbit
Application
WB 1:500-1:2000; IHC 1:50-1:200; IF 1:50-1:200
Immunogen
A phospho specific peptide corresponding to residues surrounding S807 of human Rb
Antibody Isotype
IgG
Specificity
Human
Cross Reactivity
Human, Mouse, Rat
Clone
CBAb267
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Alternative Name
RB1; OSRC; PPP1R130; RB; p105-Rb; pRb; pp110; RB transcriptional corepressor 1
Entrez Gene ID
UniProt ID
Cat CBMAB-Ab267-LY
Conjugates
Size
Price $
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