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Mouse Anti-PIGB Recombinant Antibody (2G7) (CBMAB-P1755-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2G7
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
PIGB (NP_004846, 80-172 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phosphatidylinositol glycan anchor biosynthesis, class B
Introduction
PIGB is a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.
Entrez Gene ID
9488
UniProt ID
Q92521
Alternative Names
Phosphatidylinositol Glycan Anchor Biosynthesis Class B; Phosphatidylinositol-Glycan Biosynthesis Class B Protein; Dol-P-Man Dependent GPI Mannosyltransferase; Phosphatidylinositol Glycan, Class B; GPI Mannosyltransferase III; GPI Mannosyltransferase 3;
Function
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
Biological Process
GPI anchor biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
MannosylationManual Assertion Based On ExperimentIDA:UniProtKB
Preassembly of GPI anchor in ER membraneTAS:Reactome
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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