Mouse Anti-PIGB Recombinant Antibody (2G7) (CBMAB-P1755-YC)

Name: Mouse Anti-PIGB Recombinant Antibody (2G7)
SKU: CBMAB-P1755-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

2G7

Application

ELISA

Immunogen

PIGB (NP_004846, 80-172 aa) partial recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

phosphatidylinositol glycan anchor biosynthesis, class B

Introduction

PIGB is a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.

Entrez Gene ID

9488

UniProt ID

Q92521

Alternative Names

Phosphatidylinositol Glycan Anchor Biosynthesis Class B; Phosphatidylinositol-Glycan Biosynthesis Class B Protein; Dol-P-Man Dependent GPI Mannosyltransferase; Phosphatidylinositol Glycan, Class B; GPI Mannosyltransferase III; GPI Mannosyltransferase 3;

Function

Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.

Biological Process

GPI anchor biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
MannosylationManual Assertion Based On ExperimentIDA:UniProtKB
Preassembly of GPI anchor in ER membraneTAS:Reactome

Cellular Location

Endoplasmic reticulum membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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