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Mouse Anti-PIGC Recombinant Antibody (1G2) (CBMAB-P1756-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphatidylinositol Glycan Anchor Biosynthesis Class C. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PIGC antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G2
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
PIGC (NP_002633, 1-54 aa) partial recombinant protein with GST tag. Immunogen sequence: MYAQPVTNTK EVKWQKVLYE RQPFPDNYVD RRFLEELRKN IHARKYQYWA VVFE
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-54

Target

Full Name
phosphatidylinositol glycan anchor biosynthesis, class C
Introduction
PIGC is an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized.
Entrez Gene ID
5279
UniProt ID
Q92535
Alternative Names
Phosphatidylinositol Glycan Anchor Biosynthesis Class C; PIG-C; GPI2; Phosphatidylinositol N-Acetylglucosaminyltransferase Subunit C; Phosphatidylinositol-Glycan Biosynthesis, Class C Protein; Phosphatidylinositol-Glycan Biosynthesis Class C Protein;
Function
Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.
Biological Process
GPI anchor biosynthetic processManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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