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Mouse Anti-PIK3C2G Recombinant Antibody (3D8) (CBMAB-P1791-YC)

Provided herein is a Mouse monoclonal antibody against Human Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PIK3C2G antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3D8
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phosphoinositide-3-kinase, class 2, gamma polypeptide
Introduction
PIK3C2G belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes.
Entrez Gene ID
5288
UniProt ID
O75747
Alternative Names
Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Gamma; Phosphoinositide-3-Kinase, Class 2, Gamma Polypeptide; PI3K-C2-Gamma; EC 2.7.1.154; Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing Gamma Polypeptide; Phosphatidylinositol 4-Phosphate 3-Kinase C2 Domain-Containing Subunit Gamma; Phosphatidylinositol-4-Phosphate 3-Kinase C2 Domain-Containing Subunit Gamma;
Function
Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity).
May play a role in SDF1A-stimulated chemotaxis (By similarity).
Biological Process
Cell migrationManual Assertion Based On ExperimentIBA:GO_Central
ChemotaxisIEA:UniProtKB-KW
Phosphatidylinositol 3-kinase signalingManual Assertion Based On ExperimentIBA:GO_Central
Phosphatidylinositol phosphate biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Phosphatidylinositol-3-phosphate biosynthetic processISS:UniProtKB
Phosphatidylinositol-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Viral RNA genome replicationManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Cellular Location
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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