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Mouse Anti-PJA1 Recombinant Antibody (CBCNR-624) (CBMAB-R0622-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNR-624
Antibody Isotype
IgG2a
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
praja ring finger 1
Introduction
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. The gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Entrez Gene ID
64219
UniProt ID
Q8NG27
Alternative Names
RNF70; PRAJA1
Function
Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity).
May be involved in protein sorting.
Biological Process
Protein catabolic processIEA:Ensembl
Cellular Location
Cytoplasm
PTM
Substrate for E2-dependent ubiquitination.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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