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Mouse Anti-TMEM115 Recombinant Antibody (3D4) (CBMAB-A6763-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3D4
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PL6 (AAH17367, 1 a.a. ~ 351 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Transmembrane Protein 115
Entrez Gene ID
11070
UniProt ID
Q12893
Alternative Names
PL6
Function
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.
Biological Process
Biological Process negative regulation of cell population proliferationSource:UniProtKB1 Publication
Biological Process protein transportSource:UniProtKB-KW
Biological Process retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumSource:UniProtKB1 Publication
Cellular Location
Golgi apparatus, Golgi stack membrane
Topology
Cytoplasmic: 1-19
Helical: 20-40
Lumenal: 41-97
Helical: 98-118
Cytoplasmic: 119-126
Helical: 127-147
Lumenal: 148-165
Helical: 166-186
Cytoplasmic: 187-351
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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