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Mouse Anti-PLCL2 Recombinant Antibody (1C7) (CBMAB-P2068-YC)

Provided herein is a Mouse monoclonal antibody against Human Phospholipase C like 2. The antibody can be used for immunoassay techniques, such as ELISA, IP, WB.
See all PLCL2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C7
Antibody Isotype
IgG2a, κ
Application
ELISA, IP, WB

Basic Information

Immunogen
PLCL2 (AAH36392, 121-210 aa) partial recombinant protein with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phospholipase C-like 2
Introduction
PLCL2 (Phospholipase C Like 2) is a protein coding gene. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics. Gene Ontology annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity. An important paralog of the gene is PLCL1.
Entrez Gene ID
UniProt ID
Alternative Names
PLCE2
Function
May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum.
Biological Process
B cell proliferation involved in immune responseIEA:Ensembl
B-1a B cell differentiationIEA:Ensembl
Gamma-aminobutyric acid signaling pathwayIEA:Ensembl
Lipid metabolic processIEA:InterPro
Negative regulation of B cell receptor signaling pathwayIEA:Ensembl
Negative regulation of cold-induced thermogenesisBy SimilarityISS:YuBioLab
Phosphatidylinositol-mediated signalingManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of receptor bindingIEA:Ensembl
Regulation of synaptic transmission, GABAergicIEA:Ensembl
Cellular Location
Cytoplasm
Predominantly localized to perinuclear areas in both myoblast and myotube C2C12 cells.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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