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Mouse Anti-PMS1 Antibody (2E11) (CBMAB-0822-YC)

Provided herein are mouse monoclonal antibodies against Human PMS1. The antibody clone 2E11 can be used for immunoassay techniques, such as ELISA and IP.
See all PMS1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E11
Antibody Isotype
IgG1
Application
ELISA, IP

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PMS1
Introduction
PMS1 (PMS1 protein homolog 1) is a protein belonging to the DNA mismatch repair mutL/hexB family. PMS1 forms heterodimers with MLH1, a known DNA mismatch repair protein and is thought to be involved in the repair of DNA mismatches. Mutations in PMS1 gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Entrez Gene ID
5378
UniProt ID
P54277
Alternative Names
MLH2; PMSL1; hPMS1; HNPCC3
Function
Probably involved in the repair of mismatches in DNA.
Biological Process
Mismatch repairManual Assertion Based On ExperimentIBA:GO_Central
Response to xenobiotic stimulusIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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