Mouse Anti-POMC Recombinant Antibody (B31.15) (CBMAB-1674-CN)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Stimulates the adrenal glands to release cortisol.
Melanocyte-stimulating hormone alpha
Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
Melanocyte-stimulating hormone beta
Increases the pigmentation of skin by increasing melanin production in melanocytes.
Beta-endorphin
Endogenous orexigenic opiate.
Met-enkephalin
Endogenous opiate.
Calcium-mediated signalingISS:ARUK-UCL
Cell-cell signalingManual Assertion Based On ExperimentIMP:UniProtKB
Cellular pigmentationManual Assertion Based On ExperimentIMP:UniProtKB
Generation of precursor metabolites and energyManual Assertion Based On ExperimentIMP:UniProtKB
Glucose homeostasisIEA:Ensembl
Killing of cells of another organismIDA:UniProtKB
Modulation of process of another organismIMP:UniProtKB
Negative regulation of tumor necrosis factor productionManual Assertion Based On ExperimentIDA:BHF-UCL
Neuropeptide signaling pathwayIEA:UniProtKB-KW
Positive regulation of cAMP-mediated signalingISS:ARUK-UCL
Positive regulation of neutrophil mediated killing of fungusIDA:UniProtKB
Positive regulation of oxytocin productionIEA:Ensembl
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:BHF-UCL
Regulation of appetiteManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of blood pressureISS:UniProtKB
Regulation of corticosterone secretionManual Assertion Based On ExperimentIBA:GO_Central
Regulation of glycogen metabolic processIEA:Ensembl
Response to melanocyte-stimulating hormoneISS:ARUK-UCL
Signal transductionManual Assertion Based On ExperimentIMP:UniProtKB
Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
Obesity, early-onset, with adrenal insufficiency and red hair (OBAIRH):
An autosomal recessive disorder characterized by early-onset obesity due to severe hyperphagia, pigmentary abnormalities, mainly pale skin and red hair, and secondary hypocortisolism.
O-glycosylated; reducing sugar is probably N-acetylgalactosamine.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Mouse Anti-POMC Recombinant Antibody (B31.15) (CAT#: CBMAB-A0936-YC)
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Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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