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Mouse Anti-POU2F3 Recombinant Antibody (6D1) (CBMAB-P2438-YC)

Provided herein is a Mouse monoclonal antibody against Human POU Class 2 Homeobox 3. The antibody can be used for immunoassay techniques, such as WB, IP, ELISA.
See all POU2F3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6D1
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
POU class 2 homeobox 3
Introduction
POU2F3 is a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer.
Entrez Gene ID
25833
UniProt ID
Q9UKI9
Alternative Names
Epoc-1; OCT-11; OCT11; OTF-11; PLA-1; PLA1; Skn-1a
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.
Biological Process
Epidermis developmentManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation by host of viral transcriptionManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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