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Mouse Anti-POU3F4 Recombinant Antibody (G-12) (CBMAB-P2442-YC)

Provided herein is a Mouse monoclonal antibody against Human POU Class 3 Homeobox 4. The antibody can be used for immunoassay techniques, such as WB, IP, IF, ELISA.
See all POU3F4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
G-12
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
POU Class 3 Homeobox 4
Introduction
POU3F4 is a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness.
Entrez Gene ID
5456
UniProt ID
P49335
Alternative Names
BRAIN-4; BRN-4; BRN4; DFN3; DFNX2; OCT-9; OTF-9; OTF9
Function
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
Biological Process
Brain developmentIEA:InterPro
Cochlea morphogenesisISS:UniProtKB
Negative regulation of mesenchymal cell apoptotic processISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Sensory perception of soundManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
Involvement in disease
Deafness, X-linked, 2 (DFNX2):
A form of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation, and progressive sensorineural deafness.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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