Mouse Anti-PPID Recombinant Antibody (4C7) (CBMAB-P2524-YC)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines.
(Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.
Cellular response to UV-AManual Assertion Based On ExperimentIMP:UniProtKB
Chaperone-mediated protein foldingManual Assertion Based On ExperimentIDA:UniProtKB
Lipid droplet organizationManual Assertion Based On ExperimentIMP:UniProtKB
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of protein secretionManual Assertion Based On ExperimentIMP:UniProtKB
Positive regulation of viral genome replicationManual Assertion Based On ExperimentIMP:UniProtKB
Protein foldingISS:UniProtKB
Protein peptidyl-prolyl isomerizationManual Assertion Based On ExperimentIDA:UniProtKB
Protein transportIEA:UniProtKB-KW
Protein-containing complex assemblyManual Assertion Based On ExperimentIDA:UniProtKB
Viral release from host cellManual Assertion Based On ExperimentTAS:UniProtKB
Nucleus, nucleolus
Nucleus, nucleoplasm
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Antibody Pairs
PPID Matched Antibody Pair (912) (CAT#: APMAB-912LY)
Related Products
Mouse Anti-PPID Recombinant Antibody (5A6) (CAT#: CBMAB-BR397LY)
PPID Matched Antibody Pair (912) (CAT#: APMAB-912LY)
Rabbit Anti-PPID Recombinant Antibody (CBWJC-4305) (CAT#: CBMAB-C5668WJ)
Mouse Anti-PPID Recombinant Antibody (CBT3852) (CAT#: V2LY-0625-LY1947)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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