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Mouse Anti-PPP2R2C Recombinant Antibody (6D1) (CBMAB-P2636-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein Phosphatase 2 Regulatory Subunit Bgamma. The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all PPP2R2C antibodies
Published Data
Fig.1 Expression of Ppp2r2c in adult mouse brain shown by hybridization to an antisense probe.
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Fig.2 Immunohistochemistry stating shows the expression of PPP2R2C in brain tumor patient samples compared with normal brain tissue.
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Fig.3 Western blot determined the knockdown effect of siRNAs for PPP2R2C.
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Fig.4 Immunohistochemistry for PPP2R2C.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
6D1
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
PPP2R2C (NP_065149, 1-110 aa) partial recombinant protein with GST tag. Immunogen sequence: MGEDTDTRKI NHSFLRDHSY VTEADIISTV EFNHTGELLA TGDKGGRVVI FQREPESKNA PHSQGEYDVY STFQSHEPEF DYLKSLEIEE KINKIKWLPQ QNAAHSLLST
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-110

Target

Full Name
protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform
Introduction
PPP2R2C belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
Entrez Gene ID
5522
UniProt ID
Q9Y2T4
Alternative Names
B55-GAMMA; B55gamma; IMYPNO; IMYPNO1; PR52; PR55G
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Cellular Location
cytosol
protein phosphatase type 2A complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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