Sign in or Register   Sign in or Register
  |  

Mouse Anti-PRCC Recombinant Antibody (PN-15) (CBMAB-P2687-YC)

Provided herein is a Mouse monoclonal antibody against Human Papillary Renal Cell Carcinoma (Translocation-Associated). The antibody can be used for immunoassay techniques, such as IHC.
See all PRCC antibodies
Published Data
Fig.1 Histopathological findings of the renal hemangioblastoma.
...View More

Summary

Host Animal
Mouse
Specificity
Human
Clone
PN-15
Antibody Isotype
IgG1, κ
Application
IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
TBS, pH 7.3-7.7, with 1% BSA, 1% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Papillary Renal Cell Carcinoma (Translocation-Associated)
Introduction
PRCC is a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation.
Entrez Gene ID
5546
UniProt ID
Q92733
Alternative Names
RCCP1; TPRC
Function
May regulate cell cycle progression through interaction with MAD2L2.
Biological Process
Cell cycleIEA:UniProtKB-KW
Regulation of cell cycleManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PRCC Recombinant Antibody (PN-15)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare