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Mouse Anti-PRKRIP1 Recombinant Antibody (3B11) (CBMAB-A7062-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3B11
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
PRKRIP1 (AAH14298, 1 a.a. ~ 184 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
PRKR interacting protein 1 (IL11 inducible)
Entrez Gene ID
79706
UniProt ID
Q9H875
Alternative Names
C114; FLJ13902; FLJ40957
Function
Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:30705154).
Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity).
Biological Process
mRNA processingIEA:UniProtKB-KW
Negative regulation of phosphorylationISS:UniProtKB
Negative regulation of protein kinase activityISS:UniProtKB
Renal system processManual Assertion Based On ExperimentIDA:UniProtKB
RNA splicingIEA:UniProtKB-KW
Cellular Location
Nucleus
Nucleus, nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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