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Mouse Anti-PRNP Recombinant Antibody (F89/160.1.5) (CBMAB-0720CQ)

This product is a mouse antibody that recognizes PRNP. The antibody F89/160.1.5 can be used for immunoassay techniques such as: ELISA, FC, IHC-P, WB.
Host Species
Mouse
Application
ELISA, FC, IHC-P, WB
Immunogen
Synthetic peptide from Cow Prion protein PrP aa 146-159 Sequence: SRPLIHFGSDYEDR
Antibody Isotype
IgG1
Specificity
Cow, Sheep, Bovine, Human, Deer, Hamster
Clone
F89/160.1.5
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
Alternative Name
CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.
Cat CBMAB-0720CQ
Conjugates
Size
Price $
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Second antibody and isotype control