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Mouse Anti-PRPF4B Recombinant Antibody (3E10) (CBMAB-P3016-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3E10
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa898-1006 from human PRPF4B (NP_003904) with GST tag.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid in PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Introduction
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).
Entrez Gene ID
8899
UniProt ID
Q13523
Alternative Names
PR4H; PRP4; PRP4H; PRP4K; dJ1013A10.1
Function
Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
Biological Process
mRNA cis splicing, via spliceosomeIEA:InterPro
mRNA splicing, via spliceosome1 PublicationIC:UniProtKB
Protein phosphorylationManual Assertion Based On ExperimentIBA:GO_Central
RNA splicingManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
PTM
Phosphorylated by Clk1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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